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Dheeraj, R.
- Invasive Aspergillus Tracheobronchitis Presenting as an Intraluminal Mass - A Rare Case
Abstract Views :186 |
PDF Views:2
Authors
Affiliations
1 Department of Pulmonary Medicine, DM Wayanad Institute of Medical Sciences, Wayanad, Kerala, IN
1 Department of Pulmonary Medicine, DM Wayanad Institute of Medical Sciences, Wayanad, Kerala, IN
Source
The Indian Practitioner, Vol 71, No 6 (2018), Pagination: 30-33Abstract
Aspergillus species are capable of producing invasive disease in patients with impaired defence. When trachea and bronchi are the sole sites of Aspergillus infection, it is called invasive aspergillus tracheobronchitis. This occurs in a small percentage of patients who have generalized or local immune disruption. This is a case of isolated invasive Aspergillus tracheobronchitis presenting as intraluminal mass mimicking bronchogenic carcinoma. Bronchoscopic biopsy showed profuse growth of Aspergillus fumigatus and the patient was treated with an antifungal drug. Repeat bronchoscopy after one month showed no evidence of Apergillus growth and there is no evidence of underlying malignancy either. We report this case because of its rarity.Keywords
Aspergillus Tracheobronchitis, Pseudomembranous Tracheobronchitis, Voriconazole.References
- Wu N, Huang Y, Li Q, Bai C, Huang HD, Yao XP. Isolated invasive Aspergillus tracheobronchitis: a clinical study of 19 cases. Clin Microbiol Infect. 2010; 16(6):689-95. doi: 10.1111/j.1469-0691.2009.02923.
- Karnak D, Avery RK, Gildea TR, Sahoo D, Mehta AC. Endobronchial fungal disease: an under-recognized entity. Respiration 2006; 74(1):88–104. [PubMed]
- Endmonds LC, Prakash UB. Lymphoma, neutropenia and wheezing in a 70-year-old man. Chest 1993; 103: 585–587.
- Onozawa M, Takahashi S, Kanamori H, et al. Pseudomembranous tracheobronchial aspergillosis. Internal Medicine Journal 2009; 39(1):65–66.
- Hiromitsu Ohta, Susumu Yamazaki, You Miura, Minoru Kanazawa, Fumikazu Sakai, Makoto Nagata. Invasive tracheobronchial aspergillosis progressing from bronchial to diffuse lung parenchymal lesions. Respirol Case Rep. 2016; 4(1): 32–34.
- Li Y, Yu F, Parsons C, Chen C, Ye M, Ye J, et al. Pseudomembranous Aspergillus tracheobronchitis: a potential for high mortality in low‐risk patients. Am. J. Med. Sci. 2013; 346(5):366–370. [PubMed]
- A Mohan, R Guleria, C Das, S K Sharma, S Mukhopadhyaya, A Nayak. Invasive Tracheobronchial Aspergillosis in an Immunocompetent Person. Am J Med Sci 2005; 329 (2): 107–109
- Routsi C, Kaltsas P, Bessis E, Rontogianni D, Kollias S, Roussos C. Airway obstruction and acute respiratory failure due to Aspergillus tracheobronchitis. Critical Care Medicine. 2004; 32(2):580–582.
- Walsh TJ, Anaissie EJ, Denning DW, et al. Treatment of aspergillosis: clinical practice guidelines of the infectious diseases society of America. Clinical Infectious Diseases 2008; 46(3):327–360.
- A Case of Congenital Pulmonary Airway Malformation
Abstract Views :327 |
PDF Views:0
Authors
Affiliations
1 Dept. of Pulmonary Medicine, DM Wayanad Institute of Medical Sciences, Wayanad, Kerala, IN
1 Dept. of Pulmonary Medicine, DM Wayanad Institute of Medical Sciences, Wayanad, Kerala, IN
Source
The Indian Practitioner, Vol 71, No 12 (2018), Pagination: 23-26Abstract
Congenital pulmonary airway malformations (CPAM) are considered part of the spectrum of bronchopulmonary foregut malformations. Diagnosis is usually made during the antenatal period and is rarely diagnosed in adults. The spectrum of clinical presentations varies from asymptomatic cases to recurrent respiratory tract infections or respiratory insufficiency in adulthood. Here we report one such case of an elderly female who presented with a history of recurrent respiratory tract infections and associated respiratory dysfunction since childhood. The aim of this article is to highlight a case of CPAM because of its rarity, especially in adulthood, and to briefly discuss the subtypes and differential diagnosis of cystic lung diseases of childhood.Keywords
Congenital Pulmonary Airway Malformation, Congenital Cystic Adenomatoid Malformation, Cystic Lung Diseases.References
- Ch’in KY, Tang MY. Congenital adenomatoid malformation of one lobe of a lung with general anasarca. Arch Pathol (Chic) 1949;48:221–29. [PubMed]
- Adzick NS, Harrison MR, Glick PL, Golbus MS, Anderson RL, Mahony BS, et al. Fetal cystic adenomatoid malformation: prenatal diagnosis and natural history. J Pediatr Surg. 1985; 20:483–88. [PubMed]
- Berrocal T, Madrid C, Novo S, Arjonilla A, Gomez-Leon N. Congenital anomalies of the tracheobronchial tree, lung, and mediastinum: embryology, radiology, and pathology. Radiographics 2004;24:e17. [PubMed]
- Cass DL, Quinn TM, Yang EY, Liechty KW, Crombleholme TM, Flake AW. Increased cell proliferation and decreased apoptosis characterize congenital cystic adenomatoid malformation of the lung. J PediatrSurg 1998; 33(7):1043-46[Medline].
- Gross GW. Pediatric chest imaging. CurrOpinRadiol 1992;4 (5): 36-43. (Pubmed)
- Priest JR, Williams GM, Hill DA, Dehner LP, Jaffé A. Pulmonary cysts in early childhood and the risk of malignancy. Pediatr. Pulmonol. 2009;44 (1): 14-30. (Pubmed)
- Granata C, Gambini C, Balducci T, Toma P, Michelazzi A, Conte M. Bronchioloalveolar carcinoma arising in congenital cystic adenomatoid malformation in a child: a case report and review on malignancies originating in congenital cystic adenomatoid malformation. PediatrPulmonol. 1998; 25(1):6266 [Medline].
- Oh BJ, Lee JS, Kim JS, Lim CM, Koh Y. Congenital cystic adenomatoid malformation of the lung in adults: clinical and CT evaluation of seven patients. Respirology 2006;11 (4):496501.
- AnningFeng, HourongCai, Qi Sun, Yifen Zhang, Lulu Chen, FanqingMeng. Congenital cystic adenomatoid malformation of lung in adults: 2 rare cases report and review of the literature. DiagnPathol. 2012; 7: 37-40 (Pubmed).